Solid nodules containing scattered fibrovascular cores
Solid nodules containing scattered fibrovascular cores

Papillary neoplasms of the breast—reviewing the spectrum
Histologically, SPC is composed of expansile solid nodules with interspersed delicate fibrovascular cores that appear to form the scaffold on which a monotonous

Spectrum of Papillary Lesions of the Breast:
Sonography is imaging technique of choice in young patient with breast mass because breast is dense and incidence of breast carcinoma is low. Photomicrograph shows a few dilated ducts (arrows) containing papillary

Solid Papillary Carcinoma of Breast: A Rare Case Report
They are low grade tumors originating from large or dilated ducts and composed of well-circumscribed solid nodules of monotonous neoplastic cells separated by a network of

Solid papillary carcinoma of the breast: A special entity
Solid papillary breast carcinoma is defined as a distinctive form of papillary carcinoma characterized by closely apposed expansile, cellular nodules with delicate

Papillary Masses of the Breast
Microscopy: Solid papillary carcinomas are characterized by expansile nodules with a solid growth pattern and inconspicuous, delicate fibrovascular cores. The proliferation is

Solid Thyroid Follicular Nodules With
Context.—. Follicular thyroid nodules can be a source of diagnostic difficulties, particularly when they display atypical features commonly associated with malignancy, such as nuclear grooves.Objective.—. To differentiate

High-Risk Lesions of the Breast: Diagnosis and Management
High-risk lesions are a heterogeneous group of breast diseases that carry a low risk of malignancy, ranging between 0.2% and 5% (Vizcaíno et al. 2001; D''Orsi et al. 2013).

Diagnostic challenges in papillary lesions of the breast
SPC is a distinctive form of PC characterised by round, well-defined nodules composed of low-grade ductal cells separated by fibrovascular cores. Some cases of SPC

Pulmonary sclerosing pneumocytoma:
Introduction. Sclerosing pneumocytoma (SP), or sclerosing hemangioma, is a rare, benign pulmonary neoplasm of uncertain etiology and pathogenesis that occurs predominantly among middle-aged women. 1, 2 SP

Cytologic hallmarks and differential diagnosis of papillary
In recent decades, there has been a significant increase in the incidence of thyroid cancer, primarily due to improved detection methods and greater public awareness

The Spectrum of Mucinous Lesions of the Breast
SPC of the breast was first reported in 1995. 64 Considered to be a low-grade breast carcinoma, it comprises solid nodules of neoplastic cells separated by inconspicuous fibrovascular cores. It mainly affects

Solid papillary carcinoma with reverse polarity of the breast
The six cases of solid papillary carcinoma consisted of multiples solid nodules, with rare thin fibrovascular cores that were difficult to highlight. In these tumors, epithelial cells may

Diagnostic Pitfalls in Breast Cancer Pathology With an
Papillary DCIS is an intraductal proliferation characterized by fibrovascular cores surmounted by malignant epithelial cells. 2, 31 – 33 The epithelial cells tend to be columnar in

The Morphological Spectrum of Papillary Renal Cell
Two cases with the presence of a biphasic pattern and containing a population of larger squamoid cells surrounded by smaller low-grade cells were compatible with BSA RCC. intermingled

Papillary lesions of the breast – review and practical issues
Solid papillary carcinoma in situ is characterized by solid cellular nodule punctuated by thin fibrovascular cores. Tumor cells are monotonous in plasmacytoid morphology, and

Pathology Outlines
Solid nodules of columnar epithelial cells, many with thin fibrovascular cores, leading to solid papillary architecture irregular nuclear contours and scattered nuclear

Benign Epithelial Tumors
A 49-year-old male patient was investigated for nodules seen at a X-ray in his left lung. On CT scan, an 18 mm nodule was seen in the posterior segment of the left upper lobe.

Papillary neoplasms of the breast including upgrade rates
The nuclei are located toward the apical aspect of the cells (reversed cell polarity), a feature most evident in the cells at the periphery of the solid nests or around the

Solid papillary carcinoma with reverse polarity of the breast
These tumors harbor specific histological and immunohistochemical features [2] and often consist of circumscribed solid nodules of epithelial cells arranged in nests or

Papillary Hyperplastic Nodule: Pitfall in the
Papillary formation can occur as a focal change or as a dominant nodule in multinodular goiter, Hashimoto thyroiditis, and Graves disease (12,17). The solitary lesions can demonstrate encapsulation and are comprised of complex

Lung Nodule Size Chart: What the Size of
part-solid nodule 6 mm or larger • CT scan at 3 to 6 months • CT scan every year for 5 years if the solid component remains smaller than 6 mm : Recommendations for multiple subsolid nodules.

Prepared byLast updated: Dr. Kurt Schaberg Lung
Papillary, arborizing fibrovascular cores covered by squamous epithelium. Can be exophytic or inverted and/or mixed with glandular parts HPV is involved in <½ of solitary

Pathology of benign and malignant neoplasms of salivary
The proliferation has thick, bulbous contours, centered around thin fibrovascular cores. SDC is characterized by solid or cystic nodules of tumor forming papillary or

Diagnostic challenges in papillary lesions of the
SPC is a distinctive form of PC characterised by round, well-defined nodules composed of low-grade ductal cells separated by fibrovascular cores. Some cases of SPC have been reported in literature as spindle cell DCIS,

Papillary neoplasm of the breast – A review and update
Solid papillary carcinoma (SPC) is characterized by expansile nodules with a solid growth pattern and inconspicuous, delicate fibrovascular cores. The proliferation of neoplastic

A new subtype of papillary ductal carcinoma in situ with tall
Histologic examination revealed the neoplasm characterized by papillary architecture consisting a proliferation of epithelial cells surrounding fibrovascular cores in both

Papillary Lesions of the Breast: An Update
Context.—Papillary lesions of the breast, characterized by the presence of arborescent fibrovascular cores that support epithelial proliferation, constitute a heterogeneous

Papillary neoplasms of the breast including upgrade rates
The tumor consists of large sclerotic fibrovascular cores (right) adjacent to a more solid and papillary proliferation (left). B Immunohistochemical staining with CK5/6 shows

Epithelioid Lesions of the Serosa | Archives of Pathology
Context.—Diagnosing epithelioid serosal lesions remains a challenge because numerous different processes—primary or secondary, benign or malignant—occur in body

Fine needle aspiration cytology of well-differentiated
The cell block showed a predominantly papillary growth pattern and a single layer of bland, cuboidal to flattened covering cells with stout, fibrovascular cores containing clusters of foamy

Bronchial Squamous Cell Papilloma Versus Squamous Cell
Grossly, the nodule was tan-white, friable, and polypoid. Histologic sections revealed a lesion composed of papillae containing fibrovascular cores lined by stratified

Papillary Lesions
The intraductal papilloma is a benign lesion which shows bilayered epithelium composed of both luminal and myoepithelial cells surmounting well-developed fibrovascular

Histopathology of Breast
(a–f) Solid papillary carcinoma: Solid papillary carcinoma is an in situ lesion showing multiple circumscribed nodules of tumour cells with scattered fibrovascular cores (a→←). The

Papillary lesions of the breast: selected
Solid papillary carcinoma. Portions of two circumscribed nodules of solid papillary carcinoma are seen. The nodules are composed of a uniform population of ovoid to spindle-shaped epithelial cells growing in a solid

6 FAQs about [Solid nodules containing scattered fibrovascular cores]
What does solid papillary carcinoma look like?
Solid papillary carcinoma. Portions of two circumscribed nodules of solid papillary carcinoma are seen. The nodules are composed of a uniform population of ovoid to spindle-shaped epithelial cells growing in a solid pattern. Fibrovascular cores are evident. Absence of myoepithelial cells within the cellular proliferation is characteristic.
What is a fibrovascular scaffold (SPC)?
Histologically, SPC is composed of expansile solid nodules with interspersed delicate fibrovascular cores that appear to form the scaffold on which a monotonous population of epithelial cells proliferate (Fig. 14). The epithelial cells show round to spindled nuclei of low to at most intermediate grade atypia.
What is a rosette-like structure in fibrovascular nodules?
Extracellular mucin, microcystic/microglandular spaces, clusters of foamy macrophages, and microcalcifications may also be present within the solid nodules [69, 75]. Often, the epithelial cells palisade around fibrovascular cores forming rosette-like structures (Fig. 16).
What causes cellular palisading around fibrovascular cores?
Cellular palisading around fibrovascular cores is common. Streaming growth pattern is frequently seen in cases with spindle cells. Microcystic spaces are occasionally present. Frequently, the solid cellular nodules lack surrounding myoepithelial cells.
What are solitary encapsulated papillary hyperplastic nodules (papillary adenoma)?
Solitary encapsulated papillary hyperplastic nodules (“papillary adenoma”) occur frequently in children and teenagers, and some are hyperfunctioning on radionuclide scan (18,19). Cystic change is common in these lesions, and on light microscopy the papillae are often oriented towards the center of the cyst.
Are intranuclear grooves present in papillary hyperplastic nodules (PTC)?
When present, the nucleoli in PTC are usually eccentrically located and inconspicuous (4). Intranuclear grooves can occur in papillary hyperplastic nodules; however, other features of papillary carcinoma such as nuclear membrane irregularities, chromatin clearing, and well-formed intranuclear inclusions are not seen (Figs. 3 C and 3 D) (2,17).
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